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It was soon discovered that the drug can be applied topically and still manage to achieve the same effect on blood vessels. Research was then carried out on bald mice that carried a gene manipulated for baldness to see if topical applications of the drug could boost hair growth. It was found that the drug managed to stimulate production of hairs after repeated applications. Soon the drug was made available for the treatment of male pattern baldness a kind of baldness that affects the vertex and frontal areas of the scalp.

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