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These anti-oxidant compounds first became renown with the discovery of the amazing action of grape seed extract and it's powerful ability as a free-radical scavenger. More recently, Japanese researchers went through the effort of testing HUNDREDS of compounds in the laboratory for their effect on the stimulation of hair growth, and they found the compounds of grape seed extract grew hair at a greater rate than the pharmaceutical preparation Minixodil. With further testing, using variations of the polyphenols, they discovered those found in apple skin polyphenols to be even more effective, nearly twice effective as Rogaine. Further, with the addition of Forskolin, another herbal extract, the effect was even greater.

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